Description：

Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay.

Chemical Information：

Molecular Weight (MW)		288.30
Formula		C16H16O5
CAS No.		517-89-5
Solubility (25°C) *	DMSO	57 mg/mL (197.71 mM)
	Water	Insoluble
	Alcohol	23 mg/mL (79.77 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.4686 mL	17.3430 mL	34.6861 mL
5 mM	0.6937 mL	3.4686 mL	6.9372 mL
10 mM	0.3469 mL	1.7343 mL	3.4686 mL
50 mM	0.0694 mL	0.3469 mL	0.6937 mL

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