Description：

SC-514 is an orally active, ATP-competitive IKK-2 inhibitor with IC50 of 3-12 μM, blocks NF-κB-dependent gene expression, does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.

Chemical Information：

Molecular Weight (MW)		224.3
Formula		C9H8N2OS2
CAS No.		354812-17-2
Solubility (25°C) *	DMSO	45 mg/mL (200.62 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	4.4583 mL	22.2916 mL	44.5831 mL
5 mM	0.8917 mL	4.4583 mL	8.9166 mL
10 mM	0.4458 mL	2.2292 mL	4.4583 mL
50 mM	0.0892 mL	0.4458 mL	0.8917 mL

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