Description：

SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.

Chemical Information：

Molecular Weight (MW)		343.42
Formula		C21H21N5
CAS No.		356559-20-1
Solubility (25°C) *	DMSO	68 mg/mL (198.0 mM)
	Water	Insoluble
	Alcohol	68 mg/mL (198.0 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.9119 mL	14.5594 mL	29.1189 mL
5 mM	0.5824 mL	2.9119 mL	5.8238 mL
10 mM	0.2912 mL	1.4559 mL	2.9119 mL
50 mM	0.0582 mL	0.2912 mL	0.5824 mL

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