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(R)-Nepicastat HCl

(R)-Nepicastat HCl

Catalog Number: CC5082 Rank: comment rank 5

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Description:

(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.

Chemical Information:

Molecular Weight (MW) 331.81
Formula

 

C14H15F2N3S.HCl

 

CAS No. 195881-94-8
Solubility (25°C) * DMSO 66 mg/mL (198.9 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.0138 mL 15.0689 mL 30.1377 mL
5 mM 0.6028 mL 3.0138 mL 6.0275 mL
10 mM 0.3014 mL 1.5069 mL 3.0138 mL
50 mM 0.0603 mL 0.3014 mL 0.6028 mL


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