Description：

AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM in cell-free assays, respectively; little activity outside the AGC kinase family.

Chemical Information：

Molecular Weight (MW)		337.85
Formula		C20H20ClN3
CAS No.		857531-00-1
Solubility (25°C) *	DMSO	68 mg/mL (201.27 mM)
	Water	Insoluble
	Alcohol	5 mg/mL (14.79 mM)

Biological Activity：

Targets IC50

Cyclosporine oxi Testosterone 6 0.19 mM 0.22 mM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.9599 mL	14.7995 mL	29.5989 mL
5 mM	0.5920 mL	2.9599 mL	5.9198 mL
10 mM	0.2960 mL	1.4799 mL	2.9599 mL
50 mM	0.0592 mL	0.2960 mL	0.5920 mL

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