Description：

AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. Phase 2.

Chemical Information：

Molecular Weight (MW)		382.24
Formula		C16H17Cl2N5O2
CAS No.		844442-38-2
Solubility (25°C) *	DMSO	10 mg/mL (26.16 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

PAFR 3.6 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6162 mL	13.0808 mL	26.1616 mL
5 mM	0.5232 mL	2.6162 mL	5.2323 mL
10 mM	0.2616 mL	1.3081 mL	2.6162 mL
50 mM	0.0523 mL	0.2616 mL	0.5232 mL

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