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PP2

PP2

Catalog Number: CC7164 Rank: comment rank 5

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Description:

PP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM in cell-free assays, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA.

Chemical Information:

Molecular Weight (MW) 301.77
Formula

 

C15H16ClN5

 

CAS No. 172889-27-9
Solubility (25°C) * DMSO 60 mg/mL (198.82 mM)
Water Insoluble
Alcohol 2 mg/mL (6.62 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.3138 mL 16.5689 mL 33.1378 mL
5 mM 0.6628 mL 3.3138 mL 6.6276 mL
10 mM 0.3314 mL 1.6569 mL 3.3138 mL
50 mM 0.0663 mL 0.3314 mL 0.6628 mL


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