Description：

Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.

Chemical Information：

Molecular Weight (MW)		700.78
Formula		C37H42F2N8O4
CAS No.		171228-49-2
Solubility (25°C) *	DMSO	100 mg/mL (142.69 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.4270 mL	7.1349 mL	14.2698 mL
5 mM	0.2854 mL	1.4270 mL	2.8540 mL
10 mM	0.1427 mL	0.7135 mL	1.4270 mL
50 mM	0.0285 mL	0.1427 mL	0.2854 mL

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