Description：

PLX4720 is a potent and selective inhibitor of B-Raf^V600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.

Chemical Information：

Molecular Weight (MW)		413.83
Formula		C17H14ClF2N3O3S
CAS No.		918505-84-7
Solubility (25°C) *	DMSO	83 mg/mL (200.56 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4165 mL	12.0823 mL	24.1645 mL
5 mM	0.4833 mL	2.4165 mL	4.8329 mL
10 mM	0.2416 mL	1.2082 mL	2.4165 mL
50 mM	0.0483 mL	0.2416 mL	0.4833 mL

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