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Pilaralisib (XL147)

Pilaralisib (XL147)

Catalog Number: CC7801 Rank: comment rank 5

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Description:

Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 541.02
Formula

 

C25H25ClN6O4S

 

CAS No. 934526-89-3
Solubility (25°C) * DMSO 100 mg/mL warmed (184.83 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8484 mL 9.2418 mL 18.4836 mL
5 mM 0.3697 mL 1.8484 mL 3.6967 mL
10 mM 0.1848 mL 0.9242 mL 1.8484 mL
50 mM 0.0370 mL 0.1848 mL 0.3697 mL


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