Description：

Picropodophyllin (PPP) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R).

Chemical Information：

Molecular Weight (MW)		414.41
Formula		C22H22O8
CAS No.		477-47-4
Solubility (25°C) *	DMSO	82 mg/mL warmed (197.87 mM)
	Water	Insoluble
	Alcohol	1 mg/mL warmed (2.41 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4131 mL	12.0653 mL	24.1307 mL
5 mM	0.4826 mL	2.4131 mL	4.8261 mL
10 mM	0.2413 mL	1.2065 mL	2.4131 mL
50 mM	0.0483 mL	0.2413 mL	0.4826 mL

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