Description：

PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and K_i of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform.

Chemical Information：

Molecular Weight (MW)		465.6
Formula		C27H31NO4S
CAS No.		1415562-82-1
Solubility (25°C) *	DMSO	93 mg/mL (199.74 mM)
	Water	Insoluble
	Alcohol	93 mg/mL (199.74 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1478 mL	10.7388 mL	21.4777 mL
5 mM	0.4296 mL	2.1478 mL	4.2955 mL
10 mM	0.2148 mL	1.0739 mL	2.1478 mL
50 mM	0.0430 mL	0.2148 mL	0.4296 mL

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