Description：

Ascomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.

Chemical Information：

Molecular Weight (MW)		792.01
Formula		C43H69NO12
CAS No.		104987-12-4
Solubility (25°C) *	DMSO	100 mg/mL (126.26 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (126.26 mM)

Biological Activity：

Targets IC50

20S proteasome 2.5 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.2626 mL	6.3131 mL	12.6261 mL
5 mM	0.2525 mL	1.2626 mL	2.5252 mL
10 mM	0.1263 mL	0.6313 mL	1.2626 mL
50 mM	0.0253 mL	0.1263 mL	0.2525 mL

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