Description：

PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM in A549 cell line, susceptible to oncogenic mutations (no activity to Y1230C mutant). Phase 1.

Chemical Information：

Molecular Weight (MW)		372.38
Formula		C19H16N8O
CAS No.		956905-27-4
Solubility (25°C) *	DMSO	5 mg/mL (13.42 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6854 mL	13.4271 mL	26.8543 mL
5 mM	0.5371 mL	2.6854 mL	5.3709 mL
10 mM	0.2685 mL	1.3427 mL	2.6854 mL
50 mM	0.0537 mL	0.2685 mL	0.5371 mL

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