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AS-605240

AS-605240

Catalog Number: CC1566 Rank: comment rank 5

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$ 259.00
$ 468.00
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Description:

AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3Kγ than PI3Kδ/β and PI3Kα in cell-free assays, respectively.

Chemical Information:

Molecular Weight (MW) 257.27
Formula

 

C12H7N3O2S

 

CAS No. 648450-29-7
Solubility (25°C) * DMSO 0.4 mg/mL (1.55 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
PI3Kδ PI3Kβ PI3Kγ
0.5 μM 75 μM 29 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.8870 mL 19.4348 mL 38.8697 mL
5 mM 0.7774 mL 3.8870 mL 7.7739 mL
10 mM 0.3887 mL 1.9435 mL 3.8870 mL
50 mM 0.0777 mL 0.3887 mL 0.7774 mL


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