Description：

Pacritinib (SB1518) is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.

Chemical Information：

Molecular Weight (MW)		472.58
Formula		C28H32N4O3
CAS No.		937272-79-2
Solubility (25°C) *	DMSO	11 mg/mL warmed (23.27 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1160 mL	10.5802 mL	21.1604 mL
5 mM	0.4232 mL	2.1160 mL	4.2321 mL
10 mM	0.2116 mL	1.0580 mL	2.1160 mL
50 mM	0.0423 mL	0.2116 mL	0.4232 mL

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