Description：

Oprozomib (ONX 0912) is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. Phase 1/2.

Chemical Information：

Molecular Weight (MW)		532.61
Formula		C25H32N4O7S
CAS No.		935888-69-0
Solubility (25°C) *	DMSO	100 mg/mL (187.75 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8775 mL	9.3877 mL	18.7755 mL
5 mM	0.3755 mL	1.8775 mL	3.7551 mL
10 mM	0.1878 mL	0.9388 mL	1.8775 mL
50 mM	0.0376 mL	0.1878 mL	0.3755 mL

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