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NVP-TNKS656

NVP-TNKS656

Catalog Number: CC7394 Rank: comment rank 5

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Description:

NVP-TNKS656 is a highly potent, selective, and orally active tankyrase inhibitor with IC50 of 6 nM for TNKS2, > 300-fold selectivity against PARP1 and PARP2.

Chemical Information:

Molecular Weight (MW) 494.58
Formula

 

C27H34N4O5

 

CAS No. 1419949-20-4
Solubility (25°C) * DMSO 100 mg/mL (202.19 mM)
Water Insoluble
Alcohol 10 mg/mL warmed (20.21 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0219 mL 10.1096 mL 20.2192 mL
5 mM 0.4044 mL 2.0219 mL 4.0438 mL
10 mM 0.2022 mL 1.0110 mL 2.0219 mL
50 mM 0.0404 mL 0.2022 mL 0.4044 mL


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