Description：

NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.

Chemical Information：

Molecular Weight (MW)		503.48
Formula		C26H20F3N7O
CAS No.		940310-85-0
Solubility (25°C) *	DMSO	101 mg/mL (200.6 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (5.95 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9862 mL	9.9309 mL	19.8618 mL
5 mM	0.3972 mL	1.9862 mL	3.9724 mL
10 mM	0.1986 mL	0.9931 mL	1.9862 mL
50 mM	0.0397 mL	0.1986 mL	0.3972 mL

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