Description：

NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.

Chemical Information：

Molecular Weight (MW)		503.42
Formula		C19H13N3O7S2.2Na
CAS No.		56932-43-5
Solubility (25°C) *	DMSO	100 mg/mL (198.64 mM)
	Water	100 mg/mL (198.64 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9864 mL	9.9321 mL	19.8641 mL
5 mM	0.3973 mL	1.9864 mL	3.9728 mL
10 mM	0.1986 mL	0.9932 mL	1.9864 mL
50 mM	0.0397 mL	0.1986 mL	0.3973 mL

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