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NSC 23766

NSC 23766

Catalog Number: CC8187 Rank: comment rank 5

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Description:

NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA.

Chemical Information:

Molecular Weight (MW) 530.96
Formula

 

C24H35N7.3HCl

 

CAS No. 1177865-17-6
Solubility (25°C) * DMSO 100 mg/mL warmed (188.33 mM)
Water 100 mg/mL warmed (188.33 mM)
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8834 mL 9.4169 mL 18.8338 mL
5 mM 0.3767 mL 1.8834 mL 3.7668 mL
10 mM 0.1883 mL 0.9417 mL 1.8834 mL
50 mM 0.0377 mL 0.1883 mL 0.3767 mL


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