Description：

Niraparib (MK-4827) is a selective inhibitor of PARP1/2 with IC50 of 3.8 nM/2.1 nM, with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It is >330-fold selective against PARP3, V-PARP and Tank1. Phase 3.

Chemical Information：

Molecular Weight (MW)		320.39
Formula		C19H20N4O
CAS No.		1038915-60-4
Solubility (25°C) *	DMSO	64 mg/mL (199.75 mM)
	Water	Insoluble
	Alcohol	64 mg/mL (199.75 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1212 mL	15.6060 mL	31.2120 mL
5 mM	0.6242 mL	3.1212 mL	6.2424 mL
10 mM	0.3121 mL	1.5606 mL	3.1212 mL
50 mM	0.0624 mL	0.3121 mL	0.6242 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last