Description：

Aprepitant is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM.

Chemical Information：

Molecular Weight (MW)		534.43
Formula		C23H21F7N4O3
CAS No.		170729-80-3
Solubility (25°C) *	DMSO	107 mg/mL (200.21 mM)
	Water	Insoluble
	Alcohol	15 mg/mL (28.06 mM)

Biological Activity：

Targets IC50

Estrogen 5.7 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8712 mL	9.3558 mL	18.7115 mL
5 mM	0.3742 mL	1.8712 mL	3.7423 mL
10 mM	0.1871 mL	0.9356 mL	1.8712 mL
50 mM	0.0374 mL	0.1871 mL	0.3742 mL

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