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Necrostatin-1

Necrostatin-1

Catalog Number: CC8193 Rank: comment rank 5

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Description:

Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells.

Chemical Information:

Molecular Weight (MW) 259.33
Formula

 

C13H13N3OS

 

CAS No. 4311-88-0
Solubility (25°C) * DMSO 51 mg/mL warmed (196.66 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.8561 mL 19.2805 mL 38.5609 mL
5 mM 0.7712 mL 3.8561 mL 7.7122 mL
10 mM 0.3856 mL 1.9280 mL 3.8561 mL
50 mM 0.0771 mL 0.3856 mL 0.7712 mL


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