Description：

A-674563 is an Akt1 inhibitor with K_i of 11 nM in cell-free assays, modest potent to PKA and >30-fold selective for Akt1 over PKC.

Chemical Information：

Molecular Weight (MW)		358.44
Formula		C22H22N4O
CAS No.		552325-73-2
Solubility (25°C) *	DMSO	72 mg/mL (200.87 mM)
	Water	72 mg/mL (200.87 mM)
	Alcohol	18 mg/mL (50.21 mM)

Biological Activity：

Targets IC50

MEK2 MEK1 17 nM 17 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7899 mL	13.9493 mL	27.8987 mL
5 mM	0.5580 mL	2.7899 mL	5.5797 mL
10 mM	0.2790 mL	1.3949 mL	2.7899 mL
50 mM	0.0558 mL	0.2790 mL	0.5580 mL

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