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MK-1775

MK-1775

Catalog Number: CC1681 Rank: comment rank 5

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Description:

MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.

Chemical Information:

Molecular Weight (MW) 500.6
Formula

 

C27H32N8O2

 

CAS No. 955365-80-7
Solubility (25°C) * DMSO 80 mg/mL (159.8 mM)
Water 0.0001 mg/mL (0.0 mM)
Alcohol 10 mg/mL (19.97 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9976 mL 9.9880 mL 19.9760 mL
5 mM 0.3995 mL 1.9976 mL 3.9952 mL
10 mM 0.1998 mL 0.9988 mL 1.9976 mL
50 mM 0.0400 mL 0.1998 mL 0.3995 mL


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