Description：

MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows pronounced growth suppressive activity in a panel of human MLL leukemia cell lines(GI50 at 250 nM-570 nM range), but only a minimal effect in human leukemia cell lines without MLL translocations.

Chemical Information：

Molecular Weight (MW)		564.63
Formula		C28H27F3N8S
CAS No.		1857417-13-0
Solubility (25°C) *	DMSO	100 mg/mL warmed (177.1 mM)
	Water	Insoluble
	Alcohol	15 mg/mL warmed (26.56 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7711 mL	8.8554 mL	17.7107 mL
5 mM	0.3542 mL	1.7711 mL	3.5421 mL
10 mM	0.1771 mL	0.8855 mL	1.7711 mL
50 mM	0.0354 mL	0.1771 mL	0.3542 mL

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