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MGCD-265

MGCD-265

Catalog Number: CC1517 Rank: comment rank 5

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Description:

MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 517.60
Formula

 

C26H20FN5O2S2

 

CAS No. 875337-44-3
Solubility (25°C) * DMSO 104 mg/mL (200.92 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9320 mL 9.6600 mL 19.3199 mL
5 mM 0.3864 mL 1.9320 mL 3.8640 mL
10 mM 0.1932 mL 0.9660 mL 1.9320 mL
50 mM 0.0386 mL 0.1932 mL 0.3864 mL


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