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Masitinib (AB1010)

Masitinib (AB1010)

Catalog Number: CC1220 Rank: comment rank 5

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Description:

Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.

Chemical Information:

Molecular Weight (MW) 498.64
Formula

 

C28H30N6OS

 

CAS No. 790299-79-5
Solubility (25°C) * DMSO 100 mg/mL (200.54 mM)
Water Insoluble
Alcohol 4 mg/mL (8.02 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0055 mL 10.0273 mL 20.0545 mL
5 mM 0.4011 mL 2.0055 mL 4.0109 mL
10 mM 0.2005 mL 1.0027 mL 2.0055 mL
50 mM 0.0401 mL 0.2005 mL 0.4011 mL


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