Description：

Luminespib (AUY-922, NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 2.

Chemical Information：

Molecular Weight (MW)		465.54
Formula		C26H31N3O5
CAS No.		747412-49-3
Solubility (25°C) *	DMSO	93 mg/mL warmed (199.76 mM)
	Water	Insoluble
	Alcohol	31 mg/mL (66.58 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1480 mL	10.7402 mL	21.4804 mL
5 mM	0.4296 mL	2.1480 mL	4.2961 mL
10 mM	0.2148 mL	1.0740 mL	2.1480 mL
50 mM	0.0430 mL	0.2148 mL	0.4296 mL

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