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Lomibuvir (VX-222, VCH-222)

Lomibuvir (VX-222, VCH-222)

Catalog Number: CC1636 Rank: comment rank 5

Size Price Qty
$ 118.00
$ 224.00
$ 679.00
Total:
    
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Description:

Lomibuvir (VX-222, VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. Phase 2.

Chemical Information:

Molecular Weight (MW) 445.61
Formula

 

C25H35NO4S

 

CAS No. 1026785-59-0
Solubility (25°C) * DMSO 89 mg/mL (199.72 mM)
Water Insoluble
Alcohol 89 mg/mL (199.72 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.2441 mL 11.2206 mL 22.4411 mL
5 mM 0.4488 mL 2.2441 mL 4.4882 mL
10 mM 0.2244 mL 1.1221 mL 2.2441 mL
50 mM 0.0449 mL 0.2244 mL 0.4488 mL


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