Description：

LGK-974 is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.

Chemical Information：

Molecular Weight (MW)		396.44
Formula		C23H20N6O
CAS No.		1243244-14-5
Solubility (25°C) *	DMSO	79 mg/mL warmed (199.27 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5224 mL	12.6122 mL	25.2245 mL
5 mM	0.5045 mL	2.5224 mL	5.0449 mL
10 mM	0.2522 mL	1.2612 mL	2.5224 mL
50 mM	0.0504 mL	0.2522 mL	0.5045 mL

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