Description：

LDN-193189 is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.

Chemical Information：

Molecular Weight (MW)		406.48
Formula		C25H22N6
CAS No.		1062368-24-4
Solubility (25°C) *	DMSO	Insoluble
	Water	Insoluble
	Alcohol	1 mg/mL (2.46 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4601 mL	12.3007 mL	24.6015 mL
5 mM	0.4920 mL	2.4601 mL	4.9203 mL
10 mM	0.2460 mL	1.2301 mL	2.4601 mL
50 mM	0.0492 mL	0.2460 mL	0.4920 mL

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