Description：

KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.

Chemical Information：

Molecular Weight (MW)		582.71
Formula		C33H34N4O4S
CAS No.		881375-00-4
Solubility (25°C) *	DMSO	0.4 mg/mL (0.68 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7161 mL	8.5806 mL	17.1612 mL
5 mM	0.3432 mL	1.7161 mL	3.4322 mL
10 mM	0.1716 mL	0.8581 mL	1.7161 mL
50 mM	0.0343 mL	0.1716 mL	0.3432 mL

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