Description：

Ki8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM, >40-fold selective for VEGFR2 than c-Kit, PDGFRα and FGFR-2, little activity to EGFR, HGFR and InsR.

Chemical Information：

Molecular Weight (MW)		469.41
Formula		C24H18F3N3O4
CAS No.		228559-41-9
Solubility (25°C) *	DMSO	47 mg/mL (100.12 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Bcl-2 < 0.010 nM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1303 mL	10.6517 mL	21.3033 mL
5 mM	0.4261 mL	2.1303 mL	4.2607 mL
10 mM	0.2130 mL	1.0652 mL	2.1303 mL
50 mM	0.0426 mL	0.2130 mL	0.4261 mL

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