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Ketoconazole

Ketoconazole

Catalog Number: CC1509 Rank: comment rank 5

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Description:

Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively.

Chemical Information:

Molecular Weight (MW) 531.43
Formula

 

C26H28Cl2N4O4

 

CAS No. 65277-42-1
Solubility (25°C) * DMSO 5 mg/mL warmed (9.4 mM)
Water Insoluble
Alcohol 7 mg/mL (13.17 mM)


Biological Activity:

Targets
IC50
mTOR
3.8 nM (Ki)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8817 mL 9.4086 mL 18.8172 mL
5 mM 0.3763 mL 1.8817 mL 3.7634 mL
10 mM 0.1882 mL 0.9409 mL 1.8817 mL
50 mM 0.0376 mL 0.1882 mL 0.3763 mL


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