Description：

JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with K_i of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors.

Chemical Information：

Molecular Weight (MW)		277.75
Formula		C14H16ClN3O
CAS No.		459168-41-3
Solubility (25°C) *	DMSO	56 mg/mL (201.62 mM)
	Water	Insoluble
	Alcohol	8 mg/mL (28.8 mM)

Biological Activity：

Targets IC50

PPARδ 6.6 (pIC50)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.6004 mL	18.0018 mL	36.0036 mL
5 mM	0.7201 mL	3.6004 mL	7.2007 mL
10 mM	0.3600 mL	1.8002 mL	3.6004 mL
50 mM	0.0720 mL	0.3600 mL	0.7201 mL

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