Description：

IOWH032 is a synthetic CFTR inhibitor with IC50 of 1.01 μM in CHO-CFTR cell based assays. Phase 2.

Chemical Information：

Molecular Weight (MW)		545.18
Formula		C22H15Br2N3O4
CAS No.		1191252-49-9
Solubility (25°C) *	DMSO	100 mg/mL (183.42 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

SRPK1 0.89 μM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8343 mL	9.1713 mL	18.3426 mL
5 mM	0.3669 mL	1.8343 mL	3.6685 mL
10 mM	0.1834 mL	0.9171 mL	1.8343 mL
50 mM	0.0367 mL	0.1834 mL	0.3669 mL

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