Description：

INO-1001 is a potent inhibitor of PARP with IC50 of <50 nM in CHO cells and a mediator of oxidant-induced myocyte dysfunction during reperfusion. Phase 2.

Chemical Information：

Molecular Weight (MW)		136.15
Formula		C7H8N2O
CAS No.		3544-24-9
Solubility (25°C) *	DMSO	27 mg/mL (198.31 mM)
	Water	Insoluble
	Alcohol	27 mg/mL (198.31 mM)

Biological Activity：

Targets IC50

DNA topoisomeras IDO1 0.44 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	7.3448 mL	36.7242 mL	73.4484 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL
50 mM	0.1469 mL	0.7345 mL	1.4690 mL

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