Description：

Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM showing improved in vitro binding as well as cellular potency/selectivity.

Chemical Information：

Molecular Weight (MW)		616.48
Formula		C31H29Cl2F2N3O4
CAS No.		1229705-06-9
Solubility (25°C) *	DMSO	100 mg/mL (162.21 mM)
	Water	Insoluble
	Alcohol	8 mg/mL warmed (12.97 mM)

Biological Activity：

Targets IC50

LMP7 ~10 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6221 mL	8.1106 mL	16.2211 mL
5 mM	0.3244 mL	1.6221 mL	3.2442 mL
10 mM	0.1622 mL	0.8111 mL	1.6221 mL
50 mM	0.0324 mL	0.1622 mL	0.3244 mL

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