Description：

Amiloride is a selective T-type calcium channel blocker, an epithelial sodium channel blocker and a selective inhibitor of urokinase plasminogen activator (uPA)(Ki=7 μM).

Chemical Information：

Molecular Weight (MW)		266.09
Formula		C6H8ClN7O.HCl
CAS No.		2016-88-8
Solubility (25°C) *	DMSO	53 mg/mL (199.18 mM)
	Water	6 mg/mL (22.54 mM)
	Alcohol	5 mg/mL (18.79 mM)

Biological Activity：

Targets IC50

IKCa1 (KCa3.1) 20 nM (Kd)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.7581 mL	18.7906 mL	37.5813 mL
5 mM	0.7516 mL	3.7581 mL	7.5163 mL
10 mM	0.3758 mL	1.8791 mL	3.7581 mL
50 mM	0.0752 mL	0.3758 mL	0.7516 mL

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