Description：

GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM in a cell-free assay, also inhibits TGF-β type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor.

Chemical Information：

Molecular Weight (MW)		425.48
Formula		C25H23N5O2
CAS No.		452342-67-5
Solubility (25°C) *	DMSO	15 mg/mL (35.25 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

STAT3 5.1 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3503 mL	11.7514 mL	23.5029 mL
5 mM	0.4701 mL	2.3503 mL	4.7006 mL
10 mM	0.2350 mL	1.1751 mL	2.3503 mL
50 mM	0.0470 mL	0.2350 mL	0.4701 mL

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