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AMG319

AMG319

Catalog Number: CC7969 Rank: comment rank 5

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$ 277.00
$ 683.00
$ 88.00
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Description:

AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.

Chemical Information:

Molecular Weight (MW) 385.4
Formula

 

C21H16FN7

 

CAS No. 1608125-21-8
Solubility (25°C) * DMSO 77 mg/mL (199.79 mM)
Water Insoluble
Alcohol 77 mg/mL (199.79 mM)


Biological Activity:

Targets
IC50
Aurora A Aurora B Aurora C
9 nM 31 nM 3.4 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5947 mL 12.9735 mL 25.9471 mL
5 mM 0.5189 mL 2.5947 mL 5.1894 mL
10 mM 0.2595 mL 1.2974 mL 2.5947 mL
50 mM 0.0519 mL 0.2595 mL 0.5189 mL


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