Description：

GSK591 (EPZ015866,GSK3203591) is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 11 nM.

Chemical Information：

Molecular Weight (MW)		380.48
Formula		C22H28N4O2
CAS No.		1616391-87-7
Solubility (25°C) *	DMSO	76 mg/mL (199.74 mM)
	Water	Insoluble
	Alcohol	76 mg/mL (199.74 mM)

Biological Activity：

Targets IC50

S1P receptor 0.033 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6283 mL	13.1413 mL	26.2826 mL
5 mM	0.5257 mL	2.6283 mL	5.2565 mL
10 mM	0.2628 mL	1.3141 mL	2.6283 mL
50 mM	0.0526 mL	0.2628 mL	0.5257 mL

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