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GSK591

GSK591

Catalog Number: CC8267 Rank: comment rank 5

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Description:

GSK591 (EPZ015866,GSK3203591) is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 11 nM.

Chemical Information:

Molecular Weight (MW) 380.48
Formula

 

C22H28N4O2

 

CAS No. 1616391-87-7
Solubility (25°C) * DMSO 76 mg/mL (199.74 mM)
Water Insoluble
Alcohol 76 mg/mL (199.74 mM)


Biological Activity:

Targets
IC50
S1P receptor
0.033 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6283 mL 13.1413 mL 26.2826 mL
5 mM 0.5257 mL 2.6283 mL 5.2565 mL
10 mM 0.2628 mL 1.3141 mL 2.6283 mL
50 mM 0.0526 mL 0.2628 mL 0.5257 mL


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