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Description:
GSK591 (EPZ015866,GSK3203591) is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 11 nM.
Chemical Information:
Molecular Weight (MW) 380.48 Formula
C22H28N4O2
CAS No. 1616391-87-7 Solubility (25°C) * DMSO 76 mg/mL (199.74 mM) Water Insoluble Alcohol 76 mg/mL (199.74 mM)
Biological Activity:
Targets IC50
S1P receptor 0.033 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.6283 mL 13.1413 mL 26.2826 mL 5 mM 0.5257 mL 2.6283 mL 5.2565 mL 10 mM 0.2628 mL 1.3141 mL 2.6283 mL 50 mM 0.0526 mL 0.2628 mL 0.5257 mL
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