Description：

GSK2193874 is an orally active, potent, and selective blocker of transient receptor potential vanilloid 4 (TRPV4) with IC50 values of 0.04 and 0.002 μM for hTRPV4 and rTRPV4, respectively.

Chemical Information：

Molecular Weight (MW)		691.62
Formula		C37H38BrF3N4O
CAS No.		1336960-13-4
Solubility (25°C) *	DMSO	100 mg/mL (144.58 mM)
	Water	Insoluble
	Alcohol	50 mg/mL warmed (72.29 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.4459 mL	7.2294 mL	14.4588 mL
5 mM	0.2892 mL	1.4459 mL	2.8918 mL
10 mM	0.1446 mL	0.7229 mL	1.4459 mL
50 mM	0.0289 mL	0.1446 mL	0.2892 mL

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