Description：

GSK\'872 (GSK2399872A) is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity.

Chemical Information：

Molecular Weight (MW)		383.49
Formula		C19H17N3O2S2
CAS No.		1346546-69-7
Solubility (25°C) *	DMSO	76 mg/mL (198.17 mM)
	Water	Insoluble
	Alcohol	40 mg/mL (104.3 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6076 mL	13.0381 mL	26.0763 mL
5 mM	0.5215 mL	2.6076 mL	5.2153 mL
10 mM	0.2608 mL	1.3038 mL	2.6076 mL
50 mM	0.0522 mL	0.2608 mL	0.5215 mL

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