Description：

GMX1778 (CHS828) is a potent and specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with IC50 and K_d of < 25 nM and 120 nM, respectively. Phase 1.

Chemical Information：

Molecular Weight (MW)		371.86
Formula		C19H22ClN5O
CAS No.		200484-11-3
Solubility (25°C) *	DMSO	74 mg/mL (198.99 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6892 mL	13.4459 mL	26.8918 mL
5 mM	0.5378 mL	2.6892 mL	5.3784 mL
10 mM	0.2689 mL	1.3446 mL	2.6892 mL
50 mM	0.0538 mL	0.2689 mL	0.5378 mL

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