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Gedatolisib (PF-05212384, PKI-587)

Gedatolisib (PF-05212384, PKI-587)

Catalog Number: CC2784 Rank: comment rank 5

Size Price Qty
$ 118.00
$ 189.00
$ 468.00
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Description:

Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.

Chemical Information:

Molecular Weight (MW) 615.73
Formula

 

C32H41N9O4

 

CAS No. 1197160-78-3
Solubility (25°C) * DMSO 2 mg/mL (3.24 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.6241 mL 8.1204 mL 16.2409 mL
5 mM 0.3248 mL 1.6241 mL 3.2482 mL
10 mM 0.1624 mL 0.8120 mL 1.6241 mL
50 mM 0.0325 mL 0.1624 mL 0.3248 mL


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