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Ganetespib (STA-9090)

Ganetespib (STA-9090)

Catalog Number: CC1315 Rank: comment rank 5

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Description:

Ganetespib (STA-9090) is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells, induces apoptosis of OSA cells while normal osteoblasts are not affected; active metabolite of STA-1474. Phase 3.

Chemical Information:

Molecular Weight (MW) 364.4
Formula

 

C20H20N4O3

 

CAS No. 888216-25-9
Solubility (25°C) * DMSO 40 mg/mL (109.76 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.7442 mL 13.7212 mL 27.4424 mL
5 mM 0.5488 mL 2.7442 mL 5.4885 mL
10 mM 0.2744 mL 1.3721 mL 2.7442 mL
50 mM 0.0549 mL 0.2744 mL 0.5488 mL


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